A Brief Introduction to Multi-Stage Trials for Developing Dynamic Treatment Regimens

Abstract

There is growing interest in developing evidence-based sequences of treatment which are able to adapt to an individual’s changing needs over time. In this talk, I introduce dynamic treatment regimens, which seek to operationalize clinical practice in the sense that they provide a set of individualized treatment recommendations, and sequential multiple-assignment randomized trials, which help scientists answer questions about dynamic treatment regimens. The talk is aimed at a clinical audience, and uses an example from the field of alcohol use disorder.

Date
Oct 22, 2021 7:30 AM — 8:30 AM
Event
Seminar for the Working Group on Clinical Research, University of Rochester Medical Center
Location
Virtual