SMARTs

A brief introduction to multi-stage trials for developing dynamic treatment regimens

A 45-minute seminar on dynamic treatment regimens (DTRs) and sequential multiple-assignment randomized trials geared towards a clinical audience.

Building effective adaptive interventions in mental health services research

The Johns Hopkins ALACRITY Center for Health and Longevity in Mental Illness hosts trainings for researchers interested in methods used in health services research. This series of videos provides an introduction to the use of SMARTs to build high-quality adaptive interventions for health services.

A brief introduction to multi-stage trials for developing dynamic treatment regimens

A 45-minute seminar on dynamic treatment regimens (DTRs) and sequential multiple-assignment randomized trials for a clinical audience.

Sequential, Multiple Assignment, Randomized Trials (SMART)

A dynamic treatment regimen (DTR) is a prespecified set of decision rules that can be used to guide important clinical decisions about treatment planning. This includes decisions concerning how to begin treatment based on a patient’s characteristics …

Budgeting SMART: Sample size and repeated measures with a cost constraint in a longitudinal sequential, multiple-assignment randomized trial

A contributed oral presentation at ENAR 2021.

Sample size and timepoint tradeoffs for comparing dynamic treatment regimens in a longitudinal SMART

A contributed oral presentation at JSM 2020.

Sample Size Considerations for Comparing Dynamic Treatment Regimens in a Sequential Multiple-Assignment Randomized Trial with a Continuous Longitudinal Outcome

Clinicians and researchers alike are increasingly interested in how best to personalize interventions. A dynamic treatment regimen is a sequence of prespecified decision rules which can be used to guide the delivery of a sequence of treatments or …

Sample size considerations for comparing dynamic treatment regimes in a SMART with a longitudinal outcome

An oral presentation given as part of an invited session at CMStatistics 2019 on "recent advances in methods for dynamic treatment regimes".

Sample size considerations for comparing dynamic treatment regimens in a sequentially-randomized trial with a continuous longitudinal outcome

A contributed oral presentation at the 2019 Society for Clinical Trials Annual Meeting.

Sample size considerations for comparing dynamic treatment regimens in a sequential multiple-assignment randomized trial with a continuous longitudinal outcome

A poster presented at the 2019 Michigan Student Symposium for Interdisciplinary Statistical Sciences.